- Contact Person : Mr. Wang Barry
- Company Name : Zhejiang Orient Gene Biotech Co., Ltd.
- Tel : 86-572-5226222
- Fax : 86-572-5226222
- Address : Zhejiang,Huzhou,Jiankang Industrial Area(medicine),Anji Economic Development Zone,Zhejiang
- Country/Region : China
- Zip : 313300
MOP One Step Rapid Test Strip
MOP One Step Rapid Test Strip
INTRODUCTION
A rapid, one step test for the qualitative detection of Opiates in human urine. For healthcare professionals including professionals at point of care sites. For in vitro diagnostic use only.
INTENDED USE
The MOP One Step Rapid Test Strip is a lateral flow chromatographic immunoassay for the detection of opiates in urine at a cut-off concentration of 300 ng/mL. This test will detect other opiates. Please refer to analytical specificity table in this package insert.
This assay provides only a preliminary analytical test result. A more specific alternate chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/mass spectrometry (GC/MS) is the preferred confirmatory method. Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are used.
SUMMARY
Opiate refers to any drug that is derived from the opium poppy, including the natural products, morphine and codeine, and the semi-synthetic drugs such as heroin. Opioid is more general, referring to any drug that acts on the opioid receptor.
Opioid analgesics comprise a large group of substances which control pain by depressing the central nervous system. Large doses of morphine can produce higher tolerance levels, physiological dependency in users, and may lead to substance abuse. Morphine is excreted unmetabolized, and is also the major metabolic product of codeine and heroin. Morphine is detectable in the urine for several days after an opiate dose.1
The MOP One Step Rapid Test Strip is a rapid urine screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of opiates in urine. The MOP One Step Rapid Test Strip yields a positive result when the concentration of opiate exceeds the 300 cutoff level.
PRINCIPLE
The MOP One Step Rapid Test Strip is an immunoassay based on the principle of competitive binding. Drugs which may be present in the urine specimen compete against the drug conjugate for binding sites on the antibody.
During testing, a urine specimen migrates upward by capillary action. Opiates, if present in the urine specimen below the cutoff concentration, will not saturate the binding sites of the antibody in the test strip. The morphine conjugate will be captured by antibody and a visible colored line will show up in the test line region. The colored line will not form in the test line region if the opiates level exceeds the cutoff concentration because it will saturate all the binding sites of anti-morphine antibodies.
A drug-positive urine specimen will not generate a colored line in the test line region because of drug competition, while a drug-negative urine specimen will generate a line in the test line region because of the absence of drug competition. To serve as a procedural control, a colored line will always appear at the control line region, indicating that proper volume of specimen has been added and membrane wicking has occurred.
MATERIALS
• Test strips
• Package insert
MOP One Step Rapid Test Strip
